Nephrin antibody (AA 451-550) (AbBy Fluor® 488)
Quick Overview for Nephrin antibody (AA 451-550) (AbBy Fluor® 488) (ABIN2177859)
Target
See all Nephrin (NPHS1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 451-550
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Cross-Reactivity
- Human
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Predicted Reactivity
- Rabbit
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Nephrin
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Isotype
- IgG
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Application Notes
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FCM 1:20-100
IF(IHC-P) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
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Alternative Name
- Nephrin
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Background
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Synonyms: CNF, NPHN, nephrin, Renal glomerulus-specific cell adhesion receptor, NPHS1
Background: Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity).
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Gene ID
- 4868
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UniProt
- O60500
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Pathways
- Regulation of Actin Filament Polymerization, Skeletal Muscle Fiber Development
Target
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