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Nephrin antibody (Tyr1210)
NPHS1
Reactivity: Human, Mouse
WB, FACS
Host: Rabbit
Polyclonal
RB28264
unconjugated
Product Details anti-Nephrin Antibody
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Target
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Nephrin (NPHS1)
(Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
Binding Specificity
All epitopes for Nephrin antibodies
AA 1191-1219, Tyr1210
Reactivity
All reactivities for Nephrin antibodies
Human, Mouse
Host
All hosts for Nephrin antibodies
Rabbit
Clonality
All clonalities for Nephrin antibodies
Polyclonal
Conjugate
All conjugates for Nephrin antibodies
This Nephrin antibody is un-conjugated
Application
All applications for Nephrin antibodies
Western Blotting (WB), Flow Cytometry (FACS)
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This Nephrin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1191-1219 amino acids from human Nephrin.
Clone
RB28264
Isotype
Ig Fraction
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Discover our top product NPHS1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:1000. WB: 1:1000. WB: 1:2000. FC: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for Nephrin
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Target
Nephrin (NPHS1)
(Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
Alternative Name
Nephrin (NPHS1 Products )
Synonyms
NPHS1 antibody, nphs1l antibody, nphs1 antibody, CNF antibody, NPHN antibody, nephrin antibody, NephrinB antibody, NPHS1, nephrin antibody, nephrosis 1, congenital, Finnish type (nephrin) antibody, NPHS1 nephrin S homeolog antibody, nephrin antibody, NPHS1 nephrin antibody, nephrosis 1, nephrin antibody, NPHS1 antibody, nphs1 antibody, nphs1.S antibody, LOC5579127 antibody, Nphs1 antibody
Background
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.
Molecular Weight
134742
Gene ID
4868
NCBI Accession
NP_004637
UniProt
O60500
Pathways
Regulation of Actin Filament Polymerization , Skeletal Muscle Fiber Development
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