Nucleostemin antibody (PE)

Catalog No. ABIN2178050

The Rabbit Polyclonal anti-Nucleostemin antibody has been validated for WB. It is suitable to detect Nucleostemin in samples from Human, Mouse and Rat.

Quick Overview for Nucleostemin antibody (PE) (ABIN2178050)

Target: Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nucleostemin antibody is conjugated to PE

Application: Western Blotting (WB)

Product Details anti-Nucleostemin Antibody (PE)

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nucleostemin

Isotype: IgG

Application Details

Application Notes: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Target Details for Nucleostemin

Target: Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

Alternative Name: Nucleostemin

Background:

Synonyms: E2 induced gene 3 protein, E2IG3, Estradiol induced nucleotide binding protein, GNL3, Guanine nucleotide binding protein like 3 nucleolar, Guanine nucleotide binding protein like 3, MGC800, NNP47, Novel nucleolar protein 47, NS, Nucleolar GTP binding protein 3, Nucleostemin, Putative nucleotide binding protein estradiol induced, C77032, GNL3_HUMAN.

Background: Nucleostemin is a protein found in the nucleoli of embryonic stem cells, adult CNS stem cells, primitive cells in the bone marrow and cancer cells. It is not in the differentiated cells of most adult tissues. It has been suggested to play a role in controlling the cell cycle progression in stem cells and cancer cells.

Gene ID: 26354