PCDHB1 antibody (AA 51-150) (Biotin)

Catalog No. ABIN2178237

This anti-PCDHB1 antibody is a Rabbit Polyclonal antibody detecting PCDHB1 in WB, ELISA, IHC (p) and IHC (fro). Suitable for Human.

Quick Overview for PCDHB1 antibody (AA 51-150) (Biotin) (ABIN2178237)

Target: PCDHB1 (Protocadherin beta 1 (PCDHB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHB1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PCDHB1 Antibody (Biotin)

Binding Specificity: AA 51-150

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDHB1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PCDHB1

Target: PCDHB1 (Protocadherin beta 1 (PCDHB1))

Alternative Name: PCDHB1

Background:

Synonyms: MGC138301, MGC138303, PCDB1_HUMAN, PCDH beta1, PCDH-beta-1, PCDHB 1, PCDHB1, Protocadherin beta 1, Protocadherin beta-1,

Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB1 (Protocadherin beta 1) is an 818 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB1) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB1 is a single-pass type I membrane protein containing six cadherin domains.