PCDHB10 antibody (Protocadherin beta 10) (Cy7)

Details for Product anti-PCDHB10 Antibody No. ABIN2178253
Antigen
Reactivity
Human
40
Host
Rabbit
36
4
Clonality
Polyclonal
Conjugate
This PCDHB10 antibody is conjugated to Cy7
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
29
22
17
12
4
3
3
1
Options
Immunogen KLH conjugated synthetic peptide derived from human PCDHB10
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name Pcdhb10 (PCDHB10 Antibody Abstract)
Background

Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated a, b and g, all of which contain multiple tandemly-arranged genes. PCDHB10 (protocadherin b10), also known as PCHB10 or PCDH-b10, is an 800 amino acid protein that is one of 16 proteins in the protocadherin b cluster. Unlike the a and g gene clusters, whose genes are spliced to downstream constant-region exons during transcription, members of the b cluster (such as PCDHB10) do not use constant-region exons to produce mRNAs. As a result, each protocadherin b gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB10 is a single-pass type I membrane protein that contains six cadherin domains.

Subcellular location: Extracellular

Synonyms: OTTHUMP00000160026, PCDBA_HUMAN, PCDH BETA10, PCDH-beta-10, PCDHB10, PCHB10,Protocadherin beta-10, Protocadherin beta-10.

Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months