PCDHB10 antibody (Protocadherin beta 10) (C-Term)

Details for Product anti-PCDHB10 Antibody No. ABIN954039
Antigen
Epitope
C-Term, AA 773-800
9
8
7
2
2
1
Reactivity
Human
40
Host
Rabbit
36
4
Clonality
Polyclonal
Conjugate
This PCDHB10 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
28
22
16
13
4
3
3
Options
Immunogen Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 773-800aa) of human PCDHB10.
Isotype Ig Fraction
Specificity This antibody detects human PCDHB10 at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Purified through a protein A column; followed by peptide affinity purification.
Antigen
Alternative Name PCDHB10 (PCDHB10 Antibody Abstract)
Background The PCDHB10 gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.Synonyms: PCDH-beta-10, Protocadherin beta-10
Gene ID 56126
NCBI Accession NP_061753
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Image no. 1 for anti-Protocadherin beta 10 (PCDHB10) (AA 773-800), (C-Term) antibody (ABIN954039) Flow cytometric analysis of Hela cells (right histogram) compared to a negative contr...
Image no. 2 for anti-Protocadherin beta 10 (PCDHB10) (AA 773-800), (C-Term) antibody (ABIN954039) Western blot analysis in Hela cell line lysates (35ug/lane) using PCDHB10 Antibody (C...