PCDHB10 antibody (Protocadherin beta 10) (HRP)

Details for Product anti-PCDHB10 Antibody No. ABIN2178255
Antigen
Reactivity
Human
40
Host
Rabbit
36
4
Clonality
Polyclonal
Conjugate
This PCDHB10 antibody is conjugated to HRP
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
28
22
17
13
4
3
2
1
Options
Immunogen KLH conjugated synthetic peptide derived from human PCDHB10
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name Pcdhb10 (PCDHB10 Antibody Abstract)
Background

Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated a, b and g, all of which contain multiple tandemly-arranged genes. PCDHB10 (protocadherin b10), also known as PCHB10 or PCDH-b10, is an 800 amino acid protein that is one of 16 proteins in the protocadherin b cluster. Unlike the a and g gene clusters, whose genes are spliced to downstream constant-region exons during transcription, members of the b cluster (such as PCDHB10) do not use constant-region exons to produce mRNAs. As a result, each protocadherin b gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB10 is a single-pass type I membrane protein that contains six cadherin domains.

Subcellular location: Extracellular

Synonyms: OTTHUMP00000160026, PCDBA_HUMAN, PCDH BETA10, PCDH-beta-10, PCDHB10, PCHB10,Protocadherin beta-10, Protocadherin beta-10.

Application Notes WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Preservative Gentamicin sulfate
Precaution of Use This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months