PISD antibody (PE)

Catalog No. ABIN2178491

The Rabbit Polyclonal anti-PISD antibody has been validated for WB. It is suitable to detect PISD in samples from Human, Mouse and Rat.

Quick Overview for PISD antibody (PE) (ABIN2178491)

Target: PISD (phosphatidylserine Decarboxylase (PISD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PISD antibody is conjugated to PE

Application: Western Blotting (WB)

Product Details anti-PISD Antibody (PE)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PISD

Isotype: IgG

Application Details

Application Notes: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Target Details for PISD

Target: PISD (phosphatidylserine Decarboxylase (PISD))

Alternative Name: PISD

Background:

Synonyms: DJ858B16, dJ858B16.2, DKFZp566G2246, Phosphatidylserine decarboxylase, Phosphatidylserine decarboxylase beta chain, Phosphatidylserine decarboxylase proenzyme, PISD, PISD_HUMAN, PSD, PSDC, PSSC.

Background: Enzymes known as phosphatidylserine decarboxylases (PSDs) catalyze the formation of phosphatidylethanolamine from phosphatidylserine via phosphatidylserine decarboxylation. Type I PSDs contain LGST motifs and are found in bacteria and eukaryotic mitochondria, whereas type II PSDs contain GGST motifs and are found in eukaryotic endomembrane systems. PISD (phosphatidylserine decarboxylase), also known as phosphatidylserine decarboxylase proenzyme, PSDC, PSD, PSSC, DJ858B16, dJ858B16.2 or DKFZp566G2246, is a 408 amino acid a type I phosphatidylserine decarboxylase that localizes to the inner mitochondrial membrane. PISD contains a conserved LGST motif which is cleaved to produce two isoforms known as PISD and PISD _. PISD is capable of forming a heterodimer and is highly expressed in liver and testis. The gene encoding PISD maps to human chromosome 22q12.2.

Gene ID: 23761