POMC antibody (AA 237-267) (PE)

Catalog No. ABIN2178604

This Rabbit Polyclonal antibody specifically detects POMC in FACS. It exhibits reactivity toward Mouse and Rat and has been mentioned in 2+ publications.

Quick Overview for POMC antibody (AA 237-267) (PE) (ABIN2178604)

Target: POMC (Proopiomelanocortin (POMC))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POMC antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-POMC Antibody (PE)

Binding Specificity: AA 237-267

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human POMC

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-POMC antibody (PE) (ABIN2178604)

Xie, Wang, Li, Chao, Yue: "Early Repeated Administration of CXCR4 Antagonist AMD3100 Dose-Dependently Improves Neuropathic Pain in Rats After L5 Spinal Nerve Ligation." in: Neurochemical research, Vol. 41, Issue 9, pp. 2289-99, (2016) (PubMed).

Chao, Lu, Lee, Chen, Wang, Yang, Cheng, Liao, Ro: "Early systemic granulocyte-colony stimulating factor treatment attenuates neuropathic pain after peripheral nerve injury." in: PLoS ONE, Vol. 7, Issue 8, pp. e43680, (2012) (PubMed).

Target Details for POMC

Target: POMC (Proopiomelanocortin (POMC))

Alternative Name: POMC

Background:

Synonyms: LPH, MSH, NPP, POC, ACTH, CLIP, Pro-opiomelanocortin, POMC, Corticotropin-lipotropin

Background: ACTH stimulates the adrenal glands to release cortisol. MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. Beta-endorphin and Met-enkephalin are endogenous opiates.

Gene ID: 5443

UniProt: P01189

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour