PSMA6 antibody (PE)

Catalog No. ABIN2178713

The Rabbit Polyclonal anti-PSMA6 antibody has been validated for WB. It is suitable to detect PSMA6 in samples from Human, Mouse and Rat.

Quick Overview for PSMA6 antibody (PE) (ABIN2178713)

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMA6 antibody is conjugated to PE

Application: Western Blotting (WB)

Product Details anti-PSMA6 Antibody (PE)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Proteasome 20S alpha 6

Isotype: IgG

Application Details

Application Notes: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Target Details for PSMA6

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Background:

Synonyms: 27 kDa prosomal protein, HC2, IOTA, Macropain iota chain, Macropain subunit iota, Multicatalytic endopeptidase complex iota chain, p27K, PROS 27, PROS27, Prosomal P27K protein, Proteasome prosome macropain subunit alpha type 6, Proteasome iota chain, Proteasome subunit alpha type 1, Proteasome subunit alpha type 6, Proteasome subunit iota, PSMA6, PSA6_HUMAN.

Background: The gene encodes a 246-amino acid polypeptide containing an RNA binding motif, a putative nuclear localization signal, and phosphorylation sites. The alpha subunits comprises the outer rings of the proteasome. Some alpha subunits contain a functional nuclear localization signal, proteasomes are found in both the nuclear and cytoplasmic compartments of the cell. Alpha subunits may constitute a physical barrier that limits access of cytosolic proteins into the inner proteolytic chamber.

Gene ID: 5687

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA