Vitamin D Receptor antibody (PE)

Catalog No. ABIN2180084

The Rabbit Polyclonal anti-Vitamin D Receptor antibody has been validated for WB. It is suitable to detect Vitamin D Receptor in samples from Human.

Quick Overview for Vitamin D Receptor antibody (PE) (ABIN2180084)

Target: Vitamin D Receptor (VDR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vitamin D Receptor antibody is conjugated to PE

Application: Western Blotting (WB)

Product Details anti-Vitamin D Receptor Antibody (PE)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Vitamin D Receptor

Isotype: IgG

Application Details

Application Notes: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Target Details for Vitamin D Receptor

Target: Vitamin D Receptor (VDR)

Alternative Name: Vitamin D Receptor/Vdr

Target Type: Chemical

Background:

Synonyms: NR1I1, PPP1R163, Vitamin D3 receptor, VDR, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1

Background: Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.

Gene ID: 7421

UniProt: P11473

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway