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Vitamin D Receptor antibody (PE)

VDR Reactivity: Human WB Host: Rabbit Polyclonal PE
Catalog No. ABIN2180084
  • Target See all Vitamin D Receptor (VDR) Antibodies
    Vitamin D Receptor (VDR)
    Reactivity
    • 91
    • 55
    • 39
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 98
    • 11
    • 1
    • 1
    Rabbit
    Clonality
    • 91
    • 20
    Polyclonal
    Conjugate
    • 57
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Vitamin D Receptor antibody is conjugated to PE
    Application
    • 85
    • 33
    • 26
    • 26
    • 15
    • 14
    • 13
    • 10
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Vitamin D Receptor
    Isotype
    IgG
    Top Product
    Discover our top product VDR Primary Antibody
  • Application Notes
    FCM: (1:20-100)
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Target
    Vitamin D Receptor (VDR)
    Alternative Name
    Vitamin D Receptor/Vdr (VDR Products)
    Target Type
    Chemical
    Background

    Synonyms: NR1I1, PPP1R163, Vitamin D3 receptor, VDR, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1

    Background: Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.

    Gene ID
    7421
    UniProt
    P11473
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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