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BCR antibody (pTyr177)

The Rabbit Polyclonal anti-BCR antibody has been validated for WB, IHC, FACS and IHC (p). It is suitable to detect BCR in samples from Human and Mouse.

Catalog No. ABIN219125

Datasheet as PDF

Quick Overview for BCR antibody (pTyr177) (ABIN219125)

Target

See all BCR Antibodies

BCR (Breakpoint Cluster Region (BCR))

Reactivity

Human, Mouse

Host

Rabbit

Clonality

Polyclonal

Conjugate

This BCR antibody is un-conjugated

Application

Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product BCR Primary Antibody

Binding Specificity
29

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2

1

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1

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1
pTyr177

Specificity

Recognizes endogenous levels of human Bcr and Bcr-Abl only when phosphorylated at tyrosine 177. Species cross-reactivity: Mouse.

Purification

Immunoaffinity purified

Immunogen

Synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Tyr177 of human Bcr. Molecular Weight:160kD (Bcr), 210kD (Bcr-Abl).

Type of Immunogen: Synthetic phospho-peptide

Isotype

IgG
anti-Breakpoint Cluster Region (BCR) (AA 139-280) antibody
BCR Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 1E11G12 unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 182-280) antibody
BCR Reactivity: Human WB, ELISA, IF, PLA Host: Mouse Monoclonal 2E5 unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr360) antibody
BCR Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 1-300) antibody
BCR Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr177) antibody
BCR Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (N-Term) antibody
BCR Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 1-1076) antibody
BCR Reactivity: Human WB, PLA Host: Rabbit Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 331-380), (pTyr360) antibody
BCR Reactivity: Human, Mouse WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr177) antibody
BCR Reactivity: Human WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr360) antibody
BCR Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

Application Notes

Approved: Flo (1:50), IHC, IHC-P, WB (1:1000)

Usage: Suitable for use in Flow Cytometry, Western Blot and Immunohistochemistry. Western Blot: 1:1000. Immunohistochemistry (Paraffin): 1:50. Flow Cytometry: 1:50.

Comment

Target Species of Antibody: Human

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol.

Handling Advice

Avoid repeat freeze-thaw cycles.

Storage

4 °C,-20 °C

Storage Comment

Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Target

BCR (Breakpoint Cluster Region (BCR))

Alternative Name

CML / BCR

Background

Name/Gene ID: BCR
Subfamily: BCR
Family: Protein Kinase

Synonyms: BCR, Acute lymphocytic leukemia, ALL, BCR1, BCR/FGFR1 chimera protein, Breakpoint cluster region, Chronic myeloid leukemia, D22S11, CML, D22S662, Philadelphia chromosome, PHL, FGFR1/BCR chimera protein

Molecular Weight

160kDa (Bcr), 210kDa (Bcr-Abl).

Gene ID

613

UniProt

P11274

Pathways

Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling