BCR antibody (pTyr177)

Catalog No. ABIN219125

The Rabbit Polyclonal anti-BCR antibody is suitable to detect BCR in samples from Human and Mouse. It has been validated for WB, IHC, FACS and IHC (p).

Quick Overview for BCR antibody (pTyr177) (ABIN219125)

Target: BCR (Breakpoint Cluster Region (BCR))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BCR Antibody

Binding Specificity: pTyr177

Specificity: Recognizes endogenous levels of human Bcr and Bcr-Abl only when phosphorylated at tyrosine 177. Species cross-reactivity: Mouse.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Tyr177 of human Bcr. Molecular Weight:160kD (Bcr), 210kD (Bcr-Abl).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: Flo (1:50), IHC, IHC-P, WB (1:1000)

Usage: Suitable for use in Flow Cytometry, Western Blot and Immunohistochemistry. Western Blot: 1:1000. Immunohistochemistry (Paraffin): 1:50. Flow Cytometry: 1:50.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for BCR

Target: BCR (Breakpoint Cluster Region (BCR))

Alternative Name: CML / BCR

Background: Name/Gene ID: BCR
Subfamily: BCR
Family: Protein Kinase

Synonyms: BCR, Acute lymphocytic leukemia, ALL, BCR1, BCR/FGFR1 chimera protein, Breakpoint cluster region, Chronic myeloid leukemia, D22S11, CML, D22S662, Philadelphia chromosome, PHL, FGFR1/BCR chimera protein

Molecular Weight: 160kDa (Bcr), 210kDa (Bcr-Abl).

Gene ID: 613

UniProt: P11274

Pathways: Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling