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CD55 antibody

CD55 Reactivity: Human WB, FACS Host: Mouse Monoclonal D17 unconjugated
Catalog No. ABIN2191983
  • Target See all CD55 Antibodies
    CD55 (Complement Decay-Accelerating Factor (CD55))
    Reactivity
    • 105
    • 32
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    Human
    Host
    • 69
    • 62
    • 6
    • 5
    • 3
    • 1
    • 1
    Mouse
    Clonality
    • 84
    • 61
    • 2
    Monoclonal
    Conjugate
    • 75
    • 15
    • 13
    • 10
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD55 antibody is un-conjugated
    Application
    • 90
    • 77
    • 42
    • 33
    • 28
    • 25
    • 17
    • 15
    • 14
    • 14
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Sterility
    0.2 μm filtered
    Clone
    D17
    Top Product
    Discover our top product CD55 Primary Antibody
  • Application Notes
    For flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.
    Restrictions
    For Research Use only
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Expiry Date
    12 months
  • Target
    CD55 (Complement Decay-Accelerating Factor (CD55))
    Alternative Name
    Cd55, Daf (CD55 Products)
    Background
    CD55, also designated decay accelerating factor (DAF), is a 60-70 kDa glycosyl-phosphatidylinositol (GPI) anchored protein. CD55 is a member of the family of proteins that protect host tissue from damage by autologous complement. CD55 was first recognized as a species restricting factor operating at the level of C3 activation. It binds C3b and C4b to inhibit formation and half-life of the C3 convertases. CD55 expression increases upon T cell activation and in the presence of phorbol esters antibodies to CD55 (e.g. monoclonal antibody D17) are mitogenic. CD55 is broadly distributed among cells in contact with serum, including both haematopoietic and non- haematopoietic cells. Although CD55 does not have an essential role in controlling hemolysis of erythrocytes, it has an important role in regulation of the deposition of C3 on nucleated cells. Aliases DAF (decay accelerating factor)
    Pathways
    Complement System, Regulation of Leukocyte Mediated Immunity
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