beta Arrestin 1 antibody (pSer412)

Catalog No. ABIN227103

This anti-beta Arrestin 1 antibody is a Mouse Monoclonal antibody detecting beta Arrestin 1 in WB, ELISA and IP. Suitable for Human, Mouse and Rat.

Quick Overview for beta Arrestin 1 antibody (pSer412) (ABIN227103)

Target: beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This beta Arrestin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-beta Arrestin 1 Antibody

Binding Specificity: pSer412

Specificity: Detects endogenous beta-arrestin 1 only when phosphorylated at Ser412. Does not cross-react with beta-arrestin 2. Species cross-reactivity: Mouse and rat.

Purification: Purified

Immunogen: Synthetic peptide (KLH coupled) corresponding to residues surrounding Ser412 of human beta-arrestin 1.

Type of Immunogen: Synthetic peptide

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, IP (1:50), WB (1:1000)

Usage: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Western Blot: 1:1000, incubate membrane with diluted antibody in 5 % BSA, 1X TBS, 0.1 % Tween-20 at 4?C with gentle shaking, overnight. Immunoprecipitation: 1:50.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for beta Arrestin 1

Target: beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

Alternative Name: ARRB1 / Beta Arrestin 1

Background: Name/Gene ID: ARRB1

Synonyms: ARRB1, Arrestin 2, Arrestin beta-1, Arb1, ARR1, Beta-arrestin-1, Arrestin, beta 1

Gene ID: 408

UniProt: P49407

Pathways: Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction