CBL antibody (pTyr731)

Catalog No. ABIN227162

The Rabbit Polyclonal anti-CBL antibody has been validated for WB. It is suitable to detect CBL in samples from Human.

Quick Overview for CBL antibody (pTyr731) (ABIN227162)

Target: CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CBL Antibody

Binding Specificity: pTyr731

Specificity: Detects overexpressed levels of Tyr731 phosphorylated c-Cbl. The antibody does not cross-react with other related tyrosine-phosphorylated proteins.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide (KLH coupled) corresponding to residues surrounding Tyr731 of human c-Cbl.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB (1:1000)

Usage: Suitable for use in Western Blot. Western Blot: 1:1000.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, BSA, 50 % glycerol.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CBL

Target: CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))

Alternative Name: c-CBL

Background: Name/Gene ID: CBL

Synonyms: CBL, C-CBL, Oncogene CBL2, RING finger protein 55, Proto-oncogene c-Cbl, RNF55, CBL2, FRA11B, NSLL

Gene ID: 867

UniProt: P22681

Pathways: TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals