ITPR2 antibody (C-Term)

Catalog No. ABIN228640

This Rabbit Polyclonal antibody specifically detects ITPR2 in IHC, WB, IP, IF and ICC. It exhibits reactivity toward Human, Rat, Mouse, Monkey and Hamster.

Quick Overview for ITPR2 antibody (C-Term) (ABIN228640)

Target: ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))

Reactivity: Human, Rat, Mouse, Monkey, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPR2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-ITPR2 Antibody

Binding Specificity: C-Term

Specificity: Directed against a synthetic peptide corresponding to the carboxy terminus of the rat Type II receptor. Species cross-reactivity: Human, mouse, hamster and monkey.

Purification: Affinity purified

Immunogen: Synthetic peptide corresponding to the carboxy terminus of the rat Type II receptor.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: ICC, IF (1:10 - 1:20), IHC, IP, WB (1:50 - 1:100)

Usage: Suitable for use in Western Blot, Immunofluorescence, Immunoprecipitation, Immunocytochemistry and Immunohistochemistry. Western Blot: 1:50-1:100 (detects a 260kD band). Immunofluorescence: 1:10-1:20. Immunohistochemistry: Paraformaldehyde or methanol fixed sections. Immunocytochemistry: Known to give positive reactivity on AR4-2J, HL-60, COS-I, HEK-293 and RBL-2H3 cell lines.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.05 % BSA, 0.005 % sodium azide, 10 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for ITPR2

Target: ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))

Alternative Name: ITPR2 / IP3 Receptor Type 2

Background: Name/Gene ID: ITPR2
Subfamily: Inositol 1,4,5-triphosphate receptor
Family: Ion Channel

Synonyms: ITPR2, IP3R 2, InsP3R2, IP3R2, InsP3R type II, IP3 receptor, InsP3R type 2, IP3 receptor isoform 2, Type 2 InsP3 receptor

Gene ID: 3709

UniProt: Q14571

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma