LIM Domain Kinase 1 antibody (pThr508)

Catalog No. ABIN228763

This Rabbit Polyclonal antibody specifically detects LIM Domain Kinase 1 in WB and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LIM Domain Kinase 1 antibody (pThr508) (ABIN228763)

Target: LIM Domain Kinase 1 (LIMK1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIM Domain Kinase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-LIM Domain Kinase 1 Antibody

Binding Specificity: pThr508

Specificity: Detects overexpressed LIMK1 and LIMK2 only when phosphorylated at threonine 508 or 505. Species cross-reactivity: Human, mouse and rat.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Thr508 of human LIMK1 (KLH coupled).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: IP (1:25), WB (1:1000)

Usage: Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 1:1000. Immunoprecipitation: 1:25.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.

Preservative: Without preservative

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for LIM Domain Kinase 1

Target: LIM Domain Kinase 1 (LIMK1)

Alternative Name: LIMK1 / LIMK

Background: Name/Gene ID: LIMK1
Subfamily: LIMK
Family: Protein Kinase

Synonyms: LIMK1, LIM domain kinase 1, Lim kinase 1, LIMK-1, LIM kinase, LIMK

Gene ID: 3984

UniProt: P53667

Pathways: Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events