CD40 antibody (N-Term) (FITC)
Quick Overview for CD40 antibody (N-Term) (FITC) (ABIN231934)
Target
See all CD40 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- N-Term
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Specificity
- Recognizes CD40 (BP50), a 48 KD type I single chain transmembrane glycoprotein expressed on normal and neoplastic B cells, but not on terminally differentiated plasma cells. CD40 antigen is also present on Hodgkin's and Reed-Sternberg cells, follicular dendritic cells, some macrophages, basal epithelial cells and endothelial cells
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Purification
- Purified
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Immunogen
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Type of Immunogen: Native protein -
Isotype
- IgG1
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Application Notes
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Approved: Flo
Usage: The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 15 mM sodium azide, 0.2 % high-grade protease free BSA as a stabilizing agent.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- CD40
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Alternative Name
- CD40
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Background
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Name/Gene ID: CD40
Family: TNF Receptor
Synonyms: CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5 -
Gene ID
- 958
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UniProt
- P25942
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Pathways
- NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Target
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