LDLR antibody (Extracellular Domain) (Biotin)

Catalog No. ABIN233320

This Rabbit Polyclonal antibody specifically detects LDLR in WB and FACS. It exhibits reactivity toward Human.

Quick Overview for LDLR antibody (Extracellular Domain) (Biotin) (ABIN233320)

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LDLR antibody is conjugated to Biotin

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-LDLR Antibody (Biotin)

Binding Specificity: Extracellular Domain

Specificity: Reacts specifically with human LDLR. Does not inhibit binding of LDL. Recognizes the 160kD band of LDLR and a 120kD band of the LDLR precursor from fibroblasts, hepatocytes, and monocytic cells cultured in the presence of lipoprotein-deficient serum.

Purification: Immunoaffinity purified

Immunogen: Specific synthetic peptide (sequence not conserved in VLDL receptor and LRP) of the LDL receptor extracellular domain (epitope between residues nos. 184-195, the linker region between repeats 4 and 5).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: Flo (1:10), WB

Usage: Suitable for use in Flow Cytometry, Western Blot and Receptor binding studies. Flow Cytometry: 1:10. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, penicillin/streptomycin for antibiotic protection.

Preservative: Streptomycin

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for LDLR

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Alternative Name: LDLR / LDL Receptor

Background: Name/Gene ID: LDLR

Synonyms: LDLR, FHC, LDL receptor, LDLCQ2

Gene ID: 3949

UniProt: P01130

Pathways: Hepatitis C, Lipid Metabolism