Lipopolysaccharides (LPS) antibody

Catalog No. ABIN235748

The Mouse Monoclonal anti-Lipopolysaccharides (LPS) antibody has been validated for PrA and DB. It is suitable to detect Lipopolysaccharides (LPS) in samples from Legionella pneumophila. There are 2+ publications available.

Quick Overview for Lipopolysaccharides (LPS) antibody (ABIN235748)

Target: Lipopolysaccharides (LPS)

Reactivity: Legionella pneumophila

Host: Mouse

Clonality: Monoclonal

Conjugate: This Lipopolysaccharides (LPS) antibody is un-conjugated

Application: Protein Assay (PrA), Dot Blot (DB)

Clone: 2F10

Product Details anti-Lipopolysaccharides (LPS) Antibody

Specificity: Reacts with LPS membrane of Legionella pneumophila. Does not cross-react with Legionella pneumophila serogroups 2, 6, 7, 10 and 11, Legionella bozemanii, Legionella lonbeachae, Legionella micdadei, Corynebacterium diphtheria, Pseudomonas fluorescens, Pseudomonas cepacia, Pseudomonas aerugenose, Bordetella pertusis, Leptospira interrogens (Australia, Pomona, Icterogemorrhagia), Toxoplasma gondii, Hemophilus, influenza (type B), Hemophilus ducreyi, Brucella abortus, Bacillus anthracis, Klebsiella pneumoniae, Listeria monocytogenes, Mycobacterium tuberculosis, Neisseria meningitides, Pasteurella multocida, Proteus vulgaris, Shigella sonnei, Staphyloccus faecalis, Streptococcus puogenes, Streptococcus pneumoniae, Yersinia pseudotuberculosis, Yersinia pestis EV76, Salmonella typhi, Escherichia coli K88 and Francisella tularensis 15. Cross-reaction with Legionella pneumophila serogroups 3 and 4 have not been tested.

Characteristics: MAb to Legionella pneumophila LPS, Monoclonal antibody to Legionella pneumophila LPS Philadelphia 1 strain

Purification: Protein G Sepharose Chromatography. Ascites

Purity: > 95 % pure (SDS PAGE)

Immunogen: Membrane fraction of Legionella pneumophila, strain Philadelphia 1

Isotype: IgG3

Application Details

Application Notes: Suitable for use in ELISA. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.1 % Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8 °C.

References for anti-Lipopolysaccharides (LPS) antibody (ABIN235748)

Jung, Herkt, Schulz, Bolte, Seidel, Scheller, Sittka-Stark, Bertrams, Schmeck: "Legionella pneumophila infection activates bystander cells differentially by bacterial and host cell vesicles." in: Scientific reports, Vol. 7, Issue 1, pp. 6301, (2019) (PubMed).

Jung, Stoiber, Herkt, Schulz, Bertrams, Schmeck: "Legionella pneumophila-Derived Outer Membrane Vesicles Promote Bacterial Replication in Macrophages." in: PLoS pathogens, Vol. 12, Issue 4, pp. e1005592, (2017) (PubMed).

Target Details for Lipopolysaccharides (LPS)

Target: Lipopolysaccharides (LPS)

Alternative Name: LPS

Target Type: Chemical