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HLA-ABC antibody (Biotin)

This Mouse Monoclonal antibody specifically detects HLA-ABC in FACS. It exhibits reactivity toward Human, Cow, Cat and Non-Human Primate.
Catalog No. ABIN238525

Quick Overview for HLA-ABC antibody (Biotin) (ABIN238525)

Target

See all HLA-ABC Antibodies
HLA-ABC

Reactivity

  • 69
  • 27
  • 19
  • 17
  • 15
  • 13
  • 12
  • 12
  • 12
  • 11
  • 7
  • 7
  • 6
  • 5
  • 2
  • 1
Human, Cow, Cat, Non-Human Primate

Host

  • 55
  • 10
  • 4
Mouse

Clonality

  • 59
  • 9
Monoclonal

Conjugate

  • 29
  • 7
  • 7
  • 5
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HLA-ABC antibody is conjugated to Biotin

Application

  • 52
  • 18
  • 17
  • 14
  • 10
  • 10
  • 9
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Clone

W6-32
  • Characteristics

    Synonyms: HLA-ABC, HLA class I histocompatibility antigen, MHC class I antigen

    Immunogen

    Membrane of human tonsil cellsRemarks: Gene Locus: 6p21. 3

    Isotype

    IgG2a
  • Application Notes

    Flow Cytometry: (1/300 starting dilution).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Phosphate buffered saline (PBS) with 15 mM Sodium Azide as preservative, approx. pH 7.4

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    Expiry Date

    12 months
  • Target

    HLA-ABC

    Alternative Name

    HLA Class I ABC

    Background

    HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta-2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules. MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types.Synonyms: HLA Class 2 ABC, Human Leukocyte antigen class I ABC, MHC class I ABC, Major Histocompatibility complex class I

    Pathways

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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