HLA-ABC antibody (APC)
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- Target See all HLA-ABC Antibodies
- HLA-ABC
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Reactivity
- Human, Baboon, Cynomolgus, Rhesus Monkey
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This HLA-ABC antibody is conjugated to APC
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Application
- Flow Cytometry (FACS)
- Characteristics
- Clone W6/32 recognizes a cell surface 45 kD non-polymorphic epitope protein shared among products of the HLA-A, B, and C loci. HLA class I antigen associated with beta 2-microglobulin are expressed by all human nucleated cells and HLA-Class I down regulation occurs frequently in many cancers which might adversely affect the clinical course of cancer and the outcome of T-cell-based immunotherapy. HLA-Class I present specific foreign antigen to CD8+ T cells which play central role against infection, tumor and also generation of autoimmune diseases.
- Purification
- Purified
- Purity
- >95 %
- Grade
- GMP Grade
- Immunogen
- Human Leukocytes
- Clone
- W6-32
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product HLA-ABC Primary Antibody
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anti-HLA-ABC (HLA-ABC) antibody
HLA-ABC Reactivity: Human, Cow, Baboon, Cat, Monkey FACS, IP, IHC (fro), WB, IHC Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human, Cow, Cat, Monkey, Primate FACS, IP, IHC (fro), IF, EIA Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human, Cow, Baboon, Cat, Monkey, Macaque, Primate, Chimpanzee FACS, IP, IHC (fro), IF, Func, EIA, DNA Mic Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibodyGMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibody (FITC)GMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 FITC
anti-HLA-ABC (HLA-ABC) antibody (PE)GMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 PE
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human, Cow FACS, IP, IHC (fro), IHC, ELISA Host: Mouse Monoclonal MEM-123 unconjugated
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human, Mouse, Non-Human Primate FACS, IF Host: Mouse Monoclonal 246-B8-E7 unconjugated
anti-HLA-ABC (HLA-ABC) antibody (Biotin)HLA-ABC Reactivity: Human, Cow, Baboon, Cynomolgus, Rhesus Monkey, Macaque, Shrew FACS Host: Mouse Monoclonal W6-32 Biotin
anti-HLA-ABC (HLA-ABC) antibody (FITC)HLA-ABC Reactivity: Human, Cow, Baboon, Cynomolgus, Rhesus Monkey, Macaque, Shrew FACS Host: Mouse Monoclonal W6-32 FITC
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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- Target
- HLA-ABC
- Alternative Name
- HLA-ABC (HLA-ABC Products)
- Synonyms
- HLAA antibody, major histocompatibility complex, class I, A antibody, HLA-A antibody
- Background
- Clone W6/32 recognizes a cell surface 45 kD non-polymorphic epitope protein shared among products of the HLA-A, B, and C loci. HLA class I antigen associated with beta 2-microglobulin are expressed by all human nucleated cells and HLA-Class I down regulation occurs frequently in many cancers which might adversely affect the clinical course of cancer and the outcome of T-cell-based immunotherapy. HLA-Class I present specific foreign antigen to CD8+ T cells which play central role against infection, tumor and also generation of autoimmune diseases.
- Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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