CEBPA antibody

Catalog No. ABIN2425668

This Rabbit Polyclonal antibody specifically detects CEBPA in ELISA and IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for CEBPA antibody (ABIN2425668)

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEBPA antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-CEBPA Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human CEBPA

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C/-80 °C

Storage Comment: Store at -20°C (regular) and -80°C (long term).

Target Details for CEBPA

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Alternative Name: CEBPA

Background: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Synonyms: CEBP, C/EBP-alpha

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation