VMP1
Reactivity: Human
WB, IF, ICC
Host: Rabbit
Polyclonal
APC
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Handling Advice
Avoid freeze / thaw cycles.
Storage
-20 °C/-80 °C
Storage Comment
Store at -20°C (regular) and -80°C (long term).
Target
VMP1
(Vacuole Membrane Protein 1 (VMP1))
Alternative Name
VMP1
Background
VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation. Synonyms: EPG3, TANGO5, TMEM49