NFKBIL2
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Handling Advice
Avoid freeze / thaw cycles.
Storage
-20 °C/-80 °C
Storage Comment
Store at -20°C (regular) and -80°C (long term).
Target
NFKBIL2
(Tonsoku-Like, DNA Repair Protein (NFKBIL2))
Alternative Name
TONSL
Background
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus. Synonyms: IKBR, NFKBIL2