NAIF1 antibody

Catalog No. ABIN2428455

This anti-NAIF1 antibody is a Rabbit Polyclonal antibody detecting NAIF1 in ELISA, WB and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for NAIF1 antibody (ABIN2428455)

Target: NAIF1 (Nuclear Apoptosis Inducing Factor 1 (NAIF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAIF1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NAIF1 Antibody

Purification: Antigen affinity purification

Immunogen: Recombinant protein of human NAIF1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C/-80 °C

Storage Comment: Store at -20°C (regular) and -80°C (long term).

Target Details for NAIF1

Target: NAIF1 (Nuclear Apoptosis Inducing Factor 1 (NAIF1))

Alternative Name: NAIF1

Background: Human NAIF1 is located on chromosome 9q34.11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region. NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken and frog, and shares no obvious homology to any known genes or proteins. NAIF1 was predominantly localized in the nucleus. Overexpression of NAIF1 inhibited cell growth and induced apoptosis. Furthermore, NAIF1 transfection caused both decreases in mitochondrial membrane potential and caspase-3 activation. In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.
Synonyms: C9orf90, bA379C10.2, RP11-379C10.2

Molecular Weight: Calculated MW: 35 kDa