ATPase Inhibitory Factor 1 antibody

Catalog No. ABIN2428909

This Rabbit Polyclonal antibody specifically detects ATPase Inhibitory Factor 1 in WB, ELISA and IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for ATPase Inhibitory Factor 1 antibody (ABIN2428909)

Target: ATPase Inhibitory Factor 1 (ATPIF1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATPase Inhibitory Factor 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ATPase Inhibitory Factor 1 Antibody

Purification: Antigen affinity purification

Immunogen: Recombinant protein of human ATPIF1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C/-80 °C

Storage Comment: Store at -20°C (regular) and -80°C (long term).

Target Details for ATPase Inhibitory Factor 1

Target: ATPase Inhibitory Factor 1 (ATPIF1)

Alternative Name: ATPIF1

Background: ATPase inhibitor, mitochondrial is an enzyme that in humans is encoded by the ATPIF1 gene. This gene encodes a mitochondrial ATPase inhibitor. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified. It prevents ATPase from switching to ATP hydrolysis during collapse of the electrochemical gradient, for example during oxygen deprivation ATP synthase inhibitor forms a one to one complex with the F1 ATPase, possibly by binding at the alpha-beta interface. It is thought to inhibit ATP synthesis by preventing the release of ATP. The inhibitor has two oligomeric states, dimer (the active state) and tetramer.
Synonyms: IP, ATPI, ATPIP

Molecular Weight: Calculated MW: 12 kDa