DCTN3 antibody

Catalog No. ABIN2429911

This Rabbit Polyclonal antibody specifically detects DCTN3 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for DCTN3 antibody (ABIN2429911)

Target: DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCTN3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-DCTN3 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human DCTN3

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DCTN3

Target: DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))

Alternative Name: DCTN3

Background: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

Pathways: M Phase