IFT74 antibody

Catalog No. ABIN2434482

The Rabbit Polyclonal anti-IFT74 antibody (ABIN2434482) specifically detects IFT74 in ELISA and WB. The antibody is reactive with Human samples.

Quick Overview for IFT74 antibody (ABIN2434482)

Target: IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFT74 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-IFT74 Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human IFT74

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IFT74

Target: IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))

Alternative Name: IFT74

Background: Capillary morphogenesis protein 1 (CMG1), also known as intraflagellar transport protein 74 (ITP74) or coiled-coil domain-containing protein 2 (CCDC2), is a 600 amino acid human homologue of IFT-71, a complex B protein supporting intraflagellar transport (IFT) in Chlamydomonas. CMG1 localizes to the cytoplasmic vesicle and is highly expressed in adult and fetal kidney and testis, with lower levels of expression in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. CMG1 has been suggested to have a role in the primary cilia of HUVEC, and it also functions as a transcriptional regulator of cyclin D2 in spermatocyte-derived cells.

Molecular Weight: Calculated MW: 69 kDa

NCBI Accession: NP_001092692

Pathways: Hedgehog Signaling, Chromatin Binding