SNRPC antibody (full length)

Catalog No. ABIN2452159

This Rat Monoclonal antibody specifically detects SNRPC in WB, IP, IHC (p), ELISA and IF. It exhibits reactivity toward Mouse and has been mentioned in 2+ publications.

Quick Overview for SNRPC antibody (full length) (ABIN2452159)

Target: SNRPC (Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This SNRPC antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunofluorescence (IF)

Clone: 4H12

Product Details anti-SNRPC Antibody

Binding Specificity: full length

Specificity: Specific to human, simian, and mouse U1C.

Cross-Reactivity (Details): Not tested for other species

Purification: Purified

Sterility: Sterile filtered

Immunogen: Recombinant GST-fused mouse U1C (full length)

Isotype: IgG2a kappa

Application Details

Application Notes: 1. Western blotting
2. Immunocytochemistry
3. Immunohistochemistry (frozen section)
4. ELISA
Other applications have not been tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol

Preservative: Azide free

Storage: -20 °C/-80 °C

Storage Comment: -20 C (For long term storage: -70 C)

References for anti-SNRPC antibody (ABIN2452159)

Pomeranz Krummel, Oubridge, Leung, Li, Nagai: "Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution." in: Nature, Vol. 458, Issue 7237, pp. 475-80, (2009) (PubMed).

Muto, Pomeranz Krummel, Oubridge, Hernandez, Robinson, Neuhaus, Nagai: "The structure and biochemical properties of the human spliceosomal protein U1C." in: Journal of molecular biology, Vol. 341, Issue 1, pp. 185-98, (2004) (PubMed).

Target Details for SNRPC

Target: SNRPC (Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC))

Alternative Name: U1 SnRNP C (U1C)

Background: The spliceosomal U1C protein is critical to the initiation and regulation of precursor messenger RNA (pre-mRNA) splicing, as part of the U1 small nuclear ribonucleoprotein particle (snRNP). U1C is needed for efficient complex formation of U1 snRNP with a 5' splice site. The antibody was produced from the hybridoma cultured in serum-free medium and purified under mild conditions by propriety chromatography processes.

UniProt: Q62241, P09234

Pathways: Ribonucleoprotein Complex Subunit Organization