RBPJL antibody

Catalog No. ABIN2458108

This Rabbit Polyclonal antibody specifically detects RBPJL in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RBPJL antibody (ABIN2458108)

Target: RBPJL (Recombination Signal Binding Protein For Immunoglobulin kappa J Region-Like (RBPJL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBPJL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RBPJL Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RBPJL.

Application Details

Application Notes: RBPJL antibody can be used for detection of RBPJL by ELISA at 1:312500. RBPJL antibody can be used for detection of RBPJL by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RBPJL antibody at -20 °C.

Target Details for RBPJL

Target: RBPJL (Recombination Signal Binding Protein For Immunoglobulin kappa J Region-Like (RBPJL))

Alternative Name: RBPJL

Background: RBPJL is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein. In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). RBPJL is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). The protein encoded by this gene is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.

Molecular Weight: 57 kDa

Gene ID: 11317

NCBI Accession: NP_055091

UniProt: Q5QPV0