Protocadherin 8 antibody

Catalog No. ABIN2458928

Product Details anti-Protocadherin 8 Antibody

Target: Protocadherin 8 (PCDH8)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Protocadherin 8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDH8.

Application Details

Application Notes: PCDH8 antibody can be used for detection of PCDH8 by ELISA at 1:312500. PCDH8 antibody can be used for detection of PCDH8 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCDH8 antibody at -20 °C.

Target Details for Protocadherin 8

Target: Protocadherin 8 (PCDH8)

Alternative Name: PCDH8 (PCDH8 Products)

Synonyms: papc antibody, xpapc antibody, protocadherin-8 antibody, ARCADLIN antibody, PAPC antibody, 1700080P15Rik antibody, Papc antibody, Arcadlin antibody, protocadherin 8 antibody, protocadherin 8 L homeolog antibody, protocadherin-8 antibody, PCDH8 antibody, pcdh8.L antibody, LOC485469 antibody, Pcdh8 antibody, LOC100155738 antibody

Background: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. PCDH8 is an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region.This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails.

Molecular Weight: 101 kDa

Gene ID: 5100

NCBI Accession: NP_116567

UniProt: O95206