Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6) antibody

Catalog No. ABIN2459203

This Rabbit Polyclonal antibody specifically detects in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6) antibody (ABIN2459203)

Target: Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HS3ST6.

Application Details

Application Notes: HS3ST6 antibody can be used for detection of HS3ST6 by ELISA at 1:12500. HS3ST6 antibody can be used for detection of HS3ST6 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HS3ST6 antibody at -20 °C.

Target Details

Target: Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6)

Alternative Name: HS3ST6

Background: HS3ST6 is a single-pass type II membrane protein. It belongs to the sulfotransferase 1 family. It transfers a sulfuryl group to heparan sulfate. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes Simplex Virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.

Molecular Weight: 35 kDa

Gene ID: 64711

NCBI Accession: NP_001009606

UniProt: Q96QI5

Pathways: Glycosaminoglycan Metabolic Process