COX3 antibody

Catalog No. ABIN2459381

Product Details anti-COX3 Antibody

Target: COX3 (COX-3) (Cytochrome C Oxidase Subunit 3 (COX-3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COX3.

Application Details

Application Notes: COX3 antibody can be used for detection of COX3 by ELISA at 1:1562500. COX3 antibody can be used for detection of COX3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store COX3 antibody at -20 °C.

Target Details for COX3

Target: COX3 (COX-3) (Cytochrome C Oxidase Subunit 3 (COX-3))

Alternative Name: COX3 (COX-3 Products)

Background: COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.

Molecular Weight: 29 kDa

Gene ID: 4514

NCBI Accession: NP_536849

UniProt: P00414