GBP2 antibody

Catalog No. ABIN2459799

Product Details anti-GBP2 Antibody

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GBP2.

Application Details

Application Notes: GBP2 antibody can be used for detection of GBP2 by ELISA at 1:312500. GBP2 antibody can be used for detection of GBP2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GBP2 antibody at -20 °C.

Target Details for GBP2

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Alternative Name: GBP2 (GBP2 Products)

Synonyms: guanylate binding protein 2 antibody, guanylate binding protein 2, interferon-inducible antibody, GTP binding protein 2 L homeolog antibody, GBP2 antibody, Gbp2 antibody, gtpbp2.L antibody

Background: GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). GBP2 is a GTPase that converts GTP to GDP and GMP. Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs). GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP.

Molecular Weight: 67 kDa

Gene ID: 2634

NCBI Accession: NP_004111

UniProt: P32456

Pathways: Cellular Response to Molecule of Bacterial Origin