SFRP2 antibody

Catalog No. ABIN2459973

The Rabbit Polyclonal anti-SFRP2 antibody (ABIN2459973) specifically detects SFRP2 in WB and ELISA. The antibody is reactive with Human, Mouse and Dog samples.

Quick Overview for SFRP2 antibody (ABIN2459973)

Target: SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))

Reactivity: Human, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFRP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SFRP2 Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SFRP2.

Application Details

Application Notes: SFRP2 antibody can be used for detection of SFRP2 by ELISA at 1:1562500. SFRP2 antibody can be used for detection of SFRP2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SFRP2 antibody at -20 °C.

Target Details for SFRP2

Target: SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))

Alternative Name: SFRP2

Background: SFRP2 is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 31 kDa

Gene ID: 6423

NCBI Accession: NP_003004

UniProt: Q96HF1

Pathways: WNT Signaling, Tube Formation, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Positive Regulation of fat Cell Differentiation