ESRRG antibody

Catalog No. ABIN2460266

The Rabbit Polyclonal anti-ESRRG antibody is suitable to detect ESRRG in samples from Human, Mouse, Rat, Dog and Zebrafish (Danio rerio). It has been validated for WB, ELISA and IHC.

Quick Overview for ESRRG antibody (ABIN2460266)

Target: ESRRG (Estrogen-Related Receptor gamma (ESRRG))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESRRG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ESRRG Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ESRRG.

Application Details

Application Notes: ESRRG antibody can be used for detection of ESRRG by ELISA at 1:62500. ESRRG antibody can be used for detection of ESRRG by western blot at 0.5&micr μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ESRRG antibody at -20 °C.

Target Details for ESRRG

Target: ESRRG (Estrogen-Related Receptor gamma (ESRRG))

Alternative Name: ESRRG

Background: ERRs, which are coexpressed with ERs in prostatic cells, could regulate cell growth and modulate ER-mediated pathways via interference on ERalpha transcription in prostatic cells. Not only PNRC2 but also the corepressor TLE1 functioned as ERRgamma coactivator in a reporter gene analysis. Transcriptional activation by ERR3 can be ligand-independent.

Molecular Weight: 48 kDa

Gene ID: 2104

NCBI Accession: NP_996318

UniProt: O75454

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway