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MYCN antibody

This Rabbit Polyclonal antibody specifically detects MYCN in WB and ELISA. It exhibits reactivity toward Human and Dog.
Catalog No. ABIN2460358

Quick Overview for MYCN antibody (ABIN2460358)

Target

See all MYCN Antibodies
MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Reactivity

  • 56
  • 41
  • 24
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Dog

Host

  • 44
  • 18
Rabbit

Clonality

  • 46
  • 16
Polyclonal

Conjugate

  • 30
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MYCN antibody is un-conjugated

Application

  • 23
  • 16
  • 13
  • 13
  • 7
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Purification

    Antibody is purified by protein A chromatography method.

    Immunogen

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MYCN.
  • Application Notes

    MYCN antibody can be used for detection of MYCN by ELISA at 1:312500. MYCN antibody can be used for detection of MYCN by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    Concentration

    1 mg/mL

    Buffer

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    Handling Advice

    As with any antibody avoid repeat freeze-thaw cycles.

    Storage

    4 °C/-20 °C

    Storage Comment

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store MYCN antibody at -20 °C.
  • Target

    MYCN (N-Myc Proto-Oncogene Protein (MYCN))

    Alternative Name

    MYCN

    Background

    MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. It is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas

    Molecular Weight

    50 kDa

    Gene ID

    4613

    NCBI Accession

    NP_005369

    UniProt

    P04198
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