ETV5 antibody

Catalog No. ABIN2460409

This Rabbit Polyclonal antibody specifically detects ETV5 in WB and ELISA. It exhibits reactivity toward Human, Mouse, Rat and Dog.

Quick Overview for ETV5 antibody (ABIN2460409)

Target: ETV5 (Ets Variant 5 (ETV5))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETV5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ETV5 Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ETV5.

Application Details

Application Notes: ETV5 antibody can be used for detection of ETV5 by ELISA at 1:62500. ETV5 antibody can be used for detection of ETV5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ETV5 antibody at -20 °C.

Target Details for ETV5

Target: ETV5 (Ets Variant 5 (ETV5))

Alternative Name: ETV5

Background: ETV5 Contains 1 ETS DNA-binding domain and belongs to the ETS family. The ETV5 gene expression is regulated by the conventional PKC (cPKC) pathway.ETV5 is subject to SUMO modification and this post-translational modification causes inhibition of transcription-enhancing activity Phosphorylated ETV5 and the actin cytoskeleton regulate CD44-mediated hyaluronan binding in myeloid cells. ERMs (ezrin/radixin/moesin) function as adaptor molecules in the interactions of adhesion receptors and intracellular tyrosine kinases. ETV5 can cooperate with c-Jun and has a role in progression of breast cancer

Molecular Weight: 58 kDa, 58 kDa

Gene ID: 2119

NCBI Accession: NP_004445

UniProt: P41161

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development