SIRT3 antibody

Catalog No. ABIN2460450

This anti-SIRT3 antibody is a Rabbit Polyclonal antibody detecting SIRT3 in WB and ELISA. Suitable for Human and Dog.

Quick Overview for SIRT3 antibody (ABIN2460450)

Target: SIRT3 (Sirtuin 3 (SIRT3))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SIRT3 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SIRT3.

Application Details

Application Notes: SIRT3 antibody can be used for detection of SIRT3 by ELISA at 1:312500. SIRT3 antibody can be used for detection of SIRT3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SIRT3 antibody at -20 °C.

Target Details for SIRT3

Target: SIRT3 (Sirtuin 3 (SIRT3))

Alternative Name: SIRT3

Background: SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family.

Molecular Weight: 44 kDa, 29 kDa

Gene ID: 23410

NCBI Accession: NP_036371

UniProt: Q9NTG7