WNT8B antibody

Catalog No. ABIN2460735

The Rabbit Polyclonal anti-WNT8B antibody (ABIN2460735) specifically detects WNT8B in WB and ELISA. The antibody is reactive with Human, Mouse, Rat and Dog samples.

Quick Overview for WNT8B antibody (ABIN2460735)

Target: WNT8B (Wingless-Type MMTV Integration Site Family, Member 8B (WNT8B))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNT8B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-WNT8B Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WNT8B.

Application Details

Application Notes: WNT8B antibody can be used for detection of WNT8B by ELISA at 1:1562500. WNT8B antibody can be used for detection of WNT8B by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store WNT8B antibody at -20 °C.

Target Details for WNT8B

Target: WNT8B (Wingless-Type MMTV Integration Site Family, Member 8B (WNT8B))

Alternative Name: WNT8B

Background: The WNT family consists of sereval secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT8B is a protein which shows 95 % , 86 % and 71 % amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95 %, 86 % and 71 % amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.

Molecular Weight: 39 kDa

Gene ID: 7479

NCBI Accession: NP_003384

UniProt: Q93098

Pathways: WNT Signaling