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TOX antibody

The Rabbit Polyclonal anti-TOX antibody has been validated for WB and ELISA. It is suitable to detect TOX in samples from Human, Mouse and Dog.
Catalog No. ABIN2460788

Quick Overview for TOX antibody (ABIN2460788)

Target

See all TOX Antibodies
TOX (Thymus High Mobility Group Box Protein (TOX))

Reactivity

  • 17
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Mouse, Dog

Host

  • 18
Rabbit

Clonality

  • 17
  • 1
Polyclonal

Conjugate

  • 14
  • 2
  • 1
  • 1
This TOX antibody is un-conjugated

Application

  • 12
  • 7
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Purification

    Antibody is purified by peptide affinity chromatography method.

    Immunogen

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TOX.
  • Application Notes

    TOX antibody can be used for detection of TOX by ELISA at 1:312500. TOX antibody can be used for detection of TOX by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    Concentration

    1 mg/mL

    Buffer

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    Handling Advice

    As with any antibody avoid repeat freeze-thaw cycles.

    Storage

    4 °C/-20 °C

    Storage Comment

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store TOX antibody at -20 °C.
  • Target

    TOX (Thymus High Mobility Group Box Protein (TOX))

    Alternative Name

    TOX

    Background

    Some high-mobility group (HMG) box proteins (e.g., LEF1) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.Some high-mobility group (HMG) box proteins (e.g., LEF1, MIM 153245) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1, MIM 163905) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.

    Molecular Weight

    58 kDa

    Gene ID

    9760

    NCBI Accession

    NP_055544

    UniProt

    O94900
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