FOXP2 antibody
Quick Overview for FOXP2 antibody (ABIN2460798)
Target
See all FOXP2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Antibody is purified by peptide affinity chromatography method.
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Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FOXP2.
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Application Notes
- FOXP2 antibody can be used for detection of FOXP2 by ELISA at 1:62500. FOXP2 antibody can be used for detection of FOXP2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Concentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store FOXP2 antibody at -20 °C.
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- FOXP2 (Forkhead Box P2 (FOXP2))
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Alternative Name
- FOXP2
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Background
- FOXP2 is an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.
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Molecular Weight
- 80 kDa, 83 kDa
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Gene ID
- 93986
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NCBI Accession
- NP_055306
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UniProt
- O15409
Target
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