CHMP3 antibody

Catalog No. ABIN2460955

This Rabbit Polyclonal antibody specifically detects CHMP3 in WB and ELISA. It exhibits reactivity toward Human, Mouse, Rat and Dog.

Quick Overview for CHMP3 antibody (ABIN2460955)

Target: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CHMP3 Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human VPS24.

Application Details

Application Notes: VPS24 antibody can be used for detection of VPS24 by ELISA at 1:12500. VPS24 antibody can be used for detection of VPS24 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store VPS24 antibody at -20 °C.

Target Details for CHMP3

Target: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Alternative Name: VPS24

Background: VPS24 encodes a protein that acts in the sorting of transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily.

Molecular Weight: 25 kDa

Gene ID: 51652

NCBI Accession: NP_057163

UniProt: Q3ZTS9