VDAC1 antibody

Catalog No. ABIN2461102

This Rabbit Polyclonal antibody specifically detects VDAC1 in WB, IHC and ELISA. It exhibits reactivity toward Human, Rat, Mouse and Dog.

Quick Overview for VDAC1 antibody (ABIN2461102)

Target: VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))

Reactivity: Human, Rat, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VDAC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-VDAC1 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human VDAC1.

Application Details

Application Notes: VDAC1 antibody can be used for detection of VDAC1 by ELISA at 1:312500. VDAC1 antibody can be used for detection of VDAC1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store VDAC1 antibody at -20 °C.

Target Details for VDAC1

Target: VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))

Alternative Name: VDAC1

Background: The voltage-dependent anion-selective channel 1 (VDAC1) functions as a channel in membranous structures for the outer mitochondrial membrane, the cell membrane, endosomes, caveolae, the sarcoplasmatic reticulum, synaptosomes, and post-synaptic density fraction. A major function of VDAC1 in the plasma membrane is that of a NADH (-ferricyanide) reductase that may be involved in the maintenance of cellular redox homeostasis.

Molecular Weight: 31 kDa

Gene ID: 7416

NCBI Accession: NP_003365

UniProt: Q5FVE7