TBPL1 antibody

Catalog No. ABIN2461203

This anti-TBPL1 antibody is a Rabbit Polyclonal antibody detecting TBPL1 in WB, ELISA and IHC. Suitable for Human, Mouse, Rat and Dog.

Quick Overview for TBPL1 antibody (ABIN2461203)

Target: TBPL1 (TBP-Like 1 (TBPL1))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBPL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TBPL1 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TBPL1.

Application Details

Application Notes: TBPL1 antibody can be used for detection of TBPL1 by ELISA at 1:312500. TBPL1 antibody can be used for detection of TBPL1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TBPL1 antibody at -20 °C.

Target Details for TBPL1

Target: TBPL1 (TBP-Like 1 (TBPL1))

Alternative Name: TBPL1

Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TBPL1 encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.

Molecular Weight: 21 kDa

Gene ID: 9519

NCBI Accession: NP_004856

UniProt: P62380