SOX9 antibody
Quick Overview for SOX9 antibody (ABIN2461620)
Target
See all SOX9 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Antibody is purified by peptide affinity chromatography method.
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Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SOX9.
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Application Notes
- SOX9 antibody can be used for detection of SOX9 by ELISA at 1:312500. SOX9 antibody can be used for detection of SOX9 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Concentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SOX9 antibody at -20 °C.
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- SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))
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Alternative Name
- SOX9
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Background
- SOX9 recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
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Molecular Weight
- 56 kDa
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Gene ID
- 6662
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NCBI Accession
- NP_000337
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UniProt
- P48436
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Pathways
- EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Target
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