PBX2 antibody

Catalog No. ABIN2461666

This Rabbit Polyclonal antibody specifically detects PBX2 in WB and ELISA. It exhibits reactivity toward Human, Mouse, Rat and Dog.

Quick Overview for PBX2 antibody (ABIN2461666)

Target: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PBX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PBX2 Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PBX2.

Application Details

Application Notes: PBX2 antibody can be used for detection of PBX2 by ELISA at 1:312500. PBX2 antibody can be used for detection of PBX2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PBX2 antibody at -20 °C.

Target Details for PBX2

Target: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Alternative Name: PBX2

Background: PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t (1,19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t (1,19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.

Molecular Weight: 46 kDa

Gene ID: 5089

NCBI Accession: NP_002577

UniProt: P40425

Pathways: Skeletal Muscle Fiber Development