PBX2 antibody (N-Term)

Catalog No. ABIN2780440

The Rabbit Polyclonal anti-PBX2 antibody (ABIN2780440) specifically detects PBX2 in WB. The antibody is reactive with Human, Mouse, Rat, Guinea Pig, Dog, Horse, Cow and Rabbit samples.

Quick Overview for PBX2 antibody (N-Term) (ABIN2780440)

Target: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Reactivity: Human, Mouse, Rat, Guinea Pig, Dog, Horse, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PBX2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PBX2 Antibody

Binding Specificity: N-Term

Purpose: PBX2 Antibody - N-terminal region

Sequence: PGGGRGGLGL VSGEPGGPGE PPGGGDPGGG SGGVPGGRGK QDIGDILQQI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PBX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PBX2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38172-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PBX2

Target: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Alternative Name: PBX2

Background:

Background Information: PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t(1,19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1,19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.

Gene Name: Pre-B-cell leukemia homeobox 2

Alternative Symbols: G17, HOX12, PBX2MHC

Protein Name: Pre-B-cell leukemia transcription factor 2

Molecular Weight: 46kDa

Gene ID: 5089

NCBI Accession: NP_002577

UniProt: P40425

Pathways: Skeletal Muscle Fiber Development