TFEB antibody
Quick Overview for TFEB antibody (ABIN2461794)
Target
See all TFEB AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Antibody is purified by protein A chromatography method.
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Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TFEB.
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Application Notes
- TFEB antibody can be used for detection of TFEB by ELISA at 1:312500. TFEB antibody can be used for detection of TFEB by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Concentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store TFEB antibody at -20 °C.
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- TFEB (Transcription Factor EB (TFEB))
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Alternative Name
- TFEB
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Background
- TFEB is a member of the basic Helix-Loop-Helix-Zipper family of transcription factors. TFEB can bind DNA as a homodimer or as a heterodimer with three closely related family members: MITF, TFE3 and TFEC. The t (6,11) (p21,q12), a translocation recently been shown to result in fusion of Alpha, a gene on 11q12, with the transcription factor gene TFEB on 6p21.This translocation ultimately leads to the development of Renal carcinomas.
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Molecular Weight
- 53 kDa
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Gene ID
- 7942
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NCBI Accession
- NP_009093
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UniProt
- P19484
Target
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